Science & Environment
When microbial DNA is scarce, new profiling method helps separate genuine signals from contamination
Source: Phys.org - latest science and technology news stories · Published
In acute, life-threatening infections, rapidly characterizing the microorganisms in a patient sample can help guide diagnosis and treatment. Computational methods known as taxonomic profilers can analyze metagenome sequencing data generated from the microorganisms' genomic inform
In acute, life-threatening infections, rapidly characterizing the microorganisms in a patient sample can help guide diagnosis and treatment. Computational methods known as taxonomic profilers can analyze metagenome sequencing data generated from the microorganisms' genomic information and compare it with reference genomes of individual microorganisms. However, taxonomic profilers are still under development and are not yet in common use.
Current methods can produce false-positive results or inaccurate abundance estimates.
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