Science & Environment
Exposed ends and bends attract DNA-cutting enzymes, live imaging reveals
Source: Phys.org - latest science and technology news stories · Published
Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University have directly visualized how enzymes find and break DNA molecules in real time. Using high-speed atomic force microscopy, the team followed individual enzymes as they moved along DNA and found tha
Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University have directly visualized how enzymes find and break DNA molecules in real time. Using high-speed atomic force microscopy, the team followed individual enzymes as they moved along DNA and found that they repeatedly returned to vulnerable regions before breaking them apart. The findings reveal how the structure of DNA influences its vulnerability to enzymatic breakdown.
The research was led by Richard Wong and his team: Jingge Yang, Yujia Qiu, Keesiang Lim and Toshio Ando. The work is published in Nature Communications.
Related stories
This new concrete is stronger and pulls CO2 from the air
Researchers have created a concrete mixture that is both stronger and capable of absorbing carbon dioxide. The best formula, combining zeolite with bamboo biochar, boosted compressive strength by 7.48% and tensile strength by 15% compared with conventional concrete. It also captu
All Top News -- ScienceDaily ·
When microbial DNA is scarce, new profiling method helps separate genuine signals from contamination
In acute, life-threatening infections, rapidly characterizing the microorganisms in a patient sample can help guide diagnosis and treatment. Computational methods known as taxonomic profilers can analyze metagenome sequencing data generated from the microorganisms' genomic inform
Phys.org - latest science and technology news stories ·
Meteor hit Oklahoma 100 million years later than previously thought
Researchers at The University of Texas at Austin have rewritten a small part of Oklahoma's geologic history with global implications for ancient life. Below the surface of the small town of Ames, Oklahoma, a meteor impact site spans miles. The crater is buried by sedimentary stra
Phys.org - latest science and technology news stories ·
New soil test could reveal how soil microbes help feed plants
Scientists have streamlined a method for measuring DNA-bound phosphorus in soil, making it cheaper and easier while preserving its accuracy. The technique could reveal how soil microbes help recycle phosphorus and ultimately support more sustainable fertilizer and nutrient manage
All Top News -- ScienceDaily ·
Why rheumatoid arthritis pain may persist even when inflammation is under control
Pain and fatigue in rheumatoid arthritis can persist even after inflammation improves, with depression, poor sleep, obesity, smoking, and chronic pain potentially helping sustain symptoms. Researchers say identifying these hidden drivers could prevent unnecessary medication chang
All Top News -- ScienceDaily ·