Science & Environment

Spatial genomics tool maps long-range DNA interactions while preserving cells' locations within tissues

Source: Phys.org - latest science and technology news stories · Published

Spatial genomics tool maps long-range DNA interactions while preserving cells' locations within tissues
Source: Phys.org - latest science and technology news stories

DNA is not randomly distributed within the nucleus but is packaged with proteins into chromatin, which is precisely folded into complex three-dimensional structures. However, scientists have not fully understood how this complex three-dimensional (3D) organization is regulated or

DNA is not randomly distributed within the nucleus but is packaged with proteins into chromatin, which is precisely folded into complex three-dimensional structures. However, scientists have not fully understood how this complex three-dimensional (3D) organization is regulated or how it changes over time.

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DNA recording system reveals how a single cell becomes a body
Science & Environment

DNA recording system reveals how a single cell becomes a body

Scientists have traced the development of a mouse embryo from its first two cells to the formation of organs, using a remarkable DNA recording system that reveals the family history of individual cells. Their findings uncover how different cell types emerge on their own schedules

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