Science & Environment
Scientists reveal how cosignaling receptors dually regulate T cell activation via phase separation
Source: Phys.org - latest science and technology news stories · Published
Previous studies have shown that upon antigen stimulation, the T cell receptor (TCR) undergoes phase separation with the kinase Lck to mediate rapid T cell activation. However, the manner in which costimulating receptors regulate this process has remained unclear.
Previous studies have shown that upon antigen stimulation, the T cell receptor (TCR) undergoes phase separation with the kinase Lck to mediate rapid T cell activation. However, the manner in which costimulating receptors regulate this process has remained unclear.
Related stories
Scientists may have finally explained why our brains and bodies are cross-wired
Scientists propose that the brain’s mysterious cross-wiring, which connects each hemisphere to the opposite side of the body, may have originated more than 500 million years ago in the visual systems of ancient fish. Rather than evolving for a specific advantage, this unusual arr
All Top News -- ScienceDaily ·
Scientists trick cancer cells into making the drugs that kill them
Scientists have developed a promising new cancer-fighting strategy that uses carbon monoxide naturally produced by tumor cells to manufacture powerful drugs inside the cancer cells themselves. Early laboratory experiments suggest the technique could selectively attack cancer whil
All Top News -- ScienceDaily ·
Scientists identify two overlooked skills that predict reading success
A massive new study reveals that intelligence plays a surprisingly limited role in children's reading success, while visual processing showed no meaningful connection at all. Instead, the strongest predictors are sound recognition, vocabulary, and background knowledge, offering n
All Top News -- ScienceDaily ·
Scientists detect signals at the smallest scale ever explored
Researchers have detected signals from the smallest distances ever probed.
feeds.bbci.co.uk ·
Scientists discover new Alzheimer’s drug that repairs DNA damage and reduces brain inflammation
Scientists have discovered that a drug originally developed for spinal cord injuries can tackle several key features of Alzheimer’s disease, including DNA damage and inflammation. Already tested for initial safety in humans, the experimental treatment could offer a faster path to
All Top News -- ScienceDaily ·