Science & Environment

Researchers develop AI tool to map microRNA binding sites on circular RNAs

Source: Phys.org - latest science and technology news stories · Published

Researchers develop AI tool to map microRNA binding sites on circular RNAs
Source: Phys.org - latest science and technology news stories

Circular RNAs (circRNAs) are loop-shaped molecules that can influence gene regulation through interactions with microRNAs (miRNAs). This matters because circRNAs can exist as different full-length isoforms, and their back-splice junction (BSJ) connects the two ends of the RNA. Tr

Circular RNAs (circRNAs) are loop-shaped molecules that can influence gene regulation through interactions with microRNAs (miRNAs). This matters because circRNAs can exist as different full-length isoforms, and their back-splice junction (BSJ) connects the two ends of the RNA. Treating a circular RNA like a linear transcript can therefore overlook sequence information near this junction.

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Too much RNA can starve cells of energy, scientists discover
Science & Environment

Too much RNA can starve cells of energy, scientists discover

Scientists have uncovered an unexpected danger lurking inside cells: too much RNA can damage the structures responsible for producing energy. A new study found that excess RNA, including the normally essential messenger RNA (mRNA), can directly disrupt mitochondria without relyin

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