Science & Environment

Local DNA motion inside the cell stays nearly constant throughout interphase

Source: Phys.org - latest science and technology news stories · Published

Local DNA motion inside the cell stays nearly constant throughout interphase
Source: Phys.org - latest science and technology news stories

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin. During interphase, the period between cell divisions, DNA is replicated and the nucleus becomes larger. At the same time, cells must continuously carry out essential

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin. During interphase, the period between cell divisions, DNA is replicated and the nucleus becomes larger. At the same time, cells must continuously carry out essential genome functions such as transcription, DNA replication and DNA repair.

How the behavior of genomic DNA is maintained during these large changes has remained unclear.

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DNA recording system reveals how a single cell becomes a body
Science & Environment

DNA recording system reveals how a single cell becomes a body

Scientists have traced the development of a mouse embryo from its first two cells to the formation of organs, using a remarkable DNA recording system that reveals the family history of individual cells. Their findings uncover how different cell types emerge on their own schedules

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