Science & Environment

Brain cells regulate cholesterol to control neuron signaling

Source: Phys.org - latest science and technology news stories · Published

Brain cells regulate cholesterol to control neuron signaling
Source: Phys.org - latest science and technology news stories

Cholesterol, a fat-like substance in the body best known for its role in cardiovascular health, also plays a key role in how neurons—foundational cells for the brain's ability to process and integrate information—communicate with one another. Now, research led by Vitaly A. Klyach

Cholesterol, a fat-like substance in the body best known for its role in cardiovascular health, also plays a key role in how neurons—foundational cells for the brain's ability to process and integrate information—communicate with one another. Now, research led by Vitaly A. Klyachko, a professor in the WashU Medicine Department of Cell Biology & Physiology, has shown that brain cells called astrocytes regulate cholesterol supply to modulate neuronal communication.

The findings are published in the Journal of Cell Biology.

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