Science & Environment

Added receptor helps CAR T cells stay in bone marrow in cancer mouse models

Source: Phys.org - latest science and technology news stories · Published

Added receptor helps CAR T cells stay in bone marrow in cancer mouse models
Source: Phys.org - latest science and technology news stories

By turning a patient's own immune cells into stronger cancer-fighting cells, CAR T-cell therapy has transformed how some blood cancers are treated. But it's been harder to extend this approach to solid tumors, including cancer that has spread to the bone.

By turning a patient's own immune cells into stronger cancer-fighting cells, CAR T-cell therapy has transformed how some blood cancers are treated. But it's been harder to extend this approach to solid tumors, including cancer that has spread to the bone.

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Molecular switch controls how cells load cargo for recycling
Science & Environment

Molecular switch controls how cells load cargo for recycling

Cells constantly recycle proteins and other cellular components. But how do they ensure that the right cargo ends up in the right recycling vesicle—one of the cell's transport carriers? A team at the University of Basel has identified a molecular switch that controls this process

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