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The molecular mechanism that regulates TMEM63B lipid scrambling
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The molecular mechanism that regulates TMEM63B lipid scrambling

TMEM63B, a mechanosensitive lipid scramblase, has an autoinhibitory domain in its C-terminal tail that helps keep it inactive under resting conditions, researchers from the Institute of Science Tokyo report. Changes to this regulatory region, particularly the Leu776 residue, reve

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