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Sustained pressure halts cancer cell migration and triggers death in 3D lab models

المصدر: Phys.org - latest science and technology news stories · نُشر

Sustained pressure halts cancer cell migration and triggers death in 3D lab models
المصدر: Phys.org - latest science and technology news stories

The growth and death of cancer cells in the lab are studied primarily in two-dimensional cell cultures. In a study published in the journal Developmental Cell on Oct. 14, researchers instead used three-dimensional models to uncover how pressure and mechanical confinement impact c

The growth and death of cancer cells in the lab are studied primarily in two-dimensional cell cultures. In a study published in the journal Developmental Cell on Oct. 14, researchers instead used three-dimensional models to uncover how pressure and mechanical confinement impact cell growth—halting the cells' metastatic behavior and ultimately leading to their death.

The findings could lead to the development of new biomarkers to predict which cancers are more likely to spread, or metastasize, and could ultimately lead to new approaches for preventing metastasis.

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Math under pressure may make a gamble's downside seem smaller
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Math under pressure may make a gamble's downside seem smaller

People who tackled arithmetic problems while stressed by a countdown clock, error buzzers and an observer nearby later gave potential losses less weight when deciding whether to accept a gamble. This finding from a new study suggests that pressure may change the balance between h

Phys.org - latest science and technology news stories ·

DNA recording system reveals how a single cell becomes a body
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DNA recording system reveals how a single cell becomes a body

Scientists have traced the development of a mouse embryo from its first two cells to the formation of organs, using a remarkable DNA recording system that reveals the family history of individual cells. Their findings uncover how different cell types emerge on their own schedules

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