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New DNA sequencing methods detect rare mutations acquired as bodies grow and age

المصدر: Phys.org - latest science and technology news stories · نُشر

New DNA sequencing methods detect rare mutations acquired as bodies grow and age
المصدر: Phys.org - latest science and technology news stories

Somatic mutations, the DNA changes that occur as our bodies grow and age, not only hold an important key to cancer but are emerging as the seeds of a wide range of common, noncancerous diseases. The Somatic Mosaicism across Human Tissues (SMaHT) Network, a National Institutes of

Somatic mutations, the DNA changes that occur as our bodies grow and age, not only hold an important key to cancer but are emerging as the seeds of a wide range of common, noncancerous diseases. The Somatic Mosaicism across Human Tissues (SMaHT) Network, a National Institutes of Health Common Fund initiative to catalog all the normal processes of somatic mutation, has published its first comprehensive benchmarking study in the journal Cell.

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DNA recording system reveals how a single cell becomes a body
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DNA recording system reveals how a single cell becomes a body

Scientists have traced the development of a mouse embryo from its first two cells to the formation of organs, using a remarkable DNA recording system that reveals the family history of individual cells. Their findings uncover how different cell types emerge on their own schedules

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