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How a harmful bacterium senses iron—and why it matters for fighting infections
المصدر: Phys.org - latest science and technology news stories · نُشر
Pseudomonas aeruginosa is a common culprit in hospital-acquired bacterial infections and is growing more resistant to antibiotics. New findings from Aaron Smith, professor of chemistry and biochemistry at UMBC, and collaborators at Oklahoma State University show how a two-protein
Pseudomonas aeruginosa is a common culprit in hospital-acquired bacterial infections and is growing more resistant to antibiotics. New findings from Aaron Smith, professor of chemistry and biochemistry at UMBC, and collaborators at Oklahoma State University show how a two-protein system inside the bacterium operates like a sensitive switch: The pair detects iron both outside and inside the cell and then rewrites large parts of the microbe's metabolism in response.
أخبار ذات صلة
Cost of Canadian wildfires could top $2 trillion over the 21st century, study shows
Failure to curb global warming now could cost future generations of Canadians trillions of dollars in wildfire impacts alone, according to a new Simon Fraser University study. The study is among the first to put a price tag on projected Canadian wildfire activity driven by climat
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Superbug P. aeruginosa uses two protein plugs to seal channels against antibiotics
A joint research team has identified a new mechanism underlying antibiotic resistance in Pseudomonas aeruginosa, a major multidrug-resistant "superbug." The discovery provides important clues for the development of new treatments for multidrug-resistant bacterial infections. The
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Long Island measurements reveal household products and buildings as major summer pollution sources
Products such as hairspray, paint and household disinfectants are increasingly causing summertime air pollution—and cities aren't accounting for it, which makes it harder to issue air quality advisories and enact regulations, new research from Colorado State University, the Unive
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'Self-blinking dyes' simplify nanoscale imaging without sacrificing precision
Nanobodies are extremely small antibody fragments that bind to specific molecules. When nanobodies are labeled with dyes, they can be used as probes to enhance super-resolution microscopy. However, conventional blinking dyes often perform poorly when attached to nanobodies, limit
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New approach to plant stress studies could yield hardier crops and medical insights
At the University of Missouri, plant scientist Ron Mittler is rewriting the playbook for how scientists study life by asking what happens when living organisms face multiple stresses at once.
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