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AlphaFold 3 predicts complex immune interactions using protein sequences alone

المصدر: Phys.org - latest science and technology news stories · نُشر

AlphaFold 3 predicts complex immune interactions using protein sequences alone
المصدر: Phys.org - latest science and technology news stories

Researchers at the Translational Genomics Research Institute (TGen), part of City of Hope, have developed a new approach using the artificial intelligence platform AlphaFold 3 to predict whether a T cell receptor will recognize a specific antigen based solely on its genetic seque

Researchers at the Translational Genomics Research Institute (TGen), part of City of Hope, have developed a new approach using the artificial intelligence platform AlphaFold 3 to predict whether a T cell receptor will recognize a specific antigen based solely on its genetic sequence. The advancement could help scientists more rapidly decode immune responses to infectious diseases, tumors and other health threats.

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Molecular imaging reveals how shape-shifting protein complex captures DNA and holds separate sections together
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Molecular imaging reveals how shape-shifting protein complex captures DNA and holds separate sections together

Researchers at Kanazawa University and the National Institute of Genetics in Japan have used high-speed atomic force microscopy to observe how a group of proteins known as Smc5/6 interacts with DNA. The images reveal how this structure opens and closes, captures DNA and brings se

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